Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-03-01
2011-03-01
Chandrakumar, Nizal S (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S209000, C548S519000
Reexamination Certificate
active
07897776
ABSTRACT:
Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of an inflammatory condition, in particular asthma. The compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof:wherein:X and Y are independently selected from —CH2— or —CH2—CH2—; Z is selected from S(O)mor Se(O)mand m is 0, 1 or 2; R1is optionally substituted heteroaryl or heterocyclic; R2is selected from the group consisting of hydrogen, C1-C6straight alkyl, and C1-C6branched alkyl, wherein all may be optionally substituted; and R3and R4are alkyl.
REFERENCES:
patent: 4954514 (1990-09-01), Kita et al.
patent: 5262439 (1993-11-01), Parthasarathy
patent: 5874478 (1999-02-01), Hendler et al.
patent: 5981603 (1999-11-01), Hendler
patent: 6121272 (2000-09-01), Almstead et al.
patent: 6121319 (2000-09-01), Somers
patent: 6147250 (2000-11-01), Somers
patent: 6670398 (2003-12-01), Edwards et al.
patent: 6852878 (2005-02-01), Meng et al.
patent: 2005/0070582 (2005-03-01), Li et al.
patent: 2005/0234046 (2005-10-01), Zhao et al.
patent: 2007/0037794 (2007-02-01), Ungashe et al.
patent: 0 348 203 (1989-12-01), None
patent: 0 405 788 (1991-01-01), None
patent: 2130975 (1972-11-01), None
patent: 2133024 (1972-11-01), None
patent: 2134810 (1972-12-01), None
patent: 2140769 (1973-01-01), None
patent: 2140771 (1973-01-01), None
patent: 2168137 (1973-08-01), None
patent: WO 91/01124 (1991-02-01), None
patent: WO 98/51662 (1998-11-01), None
patent: WO 01/70757 (2001-09-01), None
patent: WO 2004/037817 (2004-05-01), None
patent: WO 2005/030721 (2005-04-01), None
Dranoff G.; Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 2004;4:11-22.
O'Byrne et al., Chronic immune activation and inflammation as the cause of malignancy. Br J Cancer 2001;85:473-783.
Balkwill et al. Inflammation and cancer: back to Virchow Lancet 2001;357:539-45.
Coussens et al. Inflammation and cancer. Nature 2002;420:860-7.
Novel Phenolic Antioxidants As Multifunctional Inhibitors of Inducible VCAM-1 Expression for Use in Atherosclerosis, Bioorganic & Med Chem Ltrs. 12(18), 2545-2548, 2002).
Meng Charles Q.
Ng Raymond
Sikorski James A.
Weingarten M. David
Zhang Wei
Chandrakumar Nizal S
King & Spalding
Salutria Pharmaceuticals LLC
LandOfFree
Sulfonamide containing compounds for treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sulfonamide containing compounds for treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sulfonamide containing compounds for treatment of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2717159