Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-08-10
1992-02-25
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548337, A61K 31415, C07D23384
Patent
active
050914030
ABSTRACT:
Disclosed are novel imidazole derivatives having the formula: ##STR1## wherein R.sup.1 is hydrogen or an alkyl group having 1-6 carbon atoms, R.sup.2 is an alkyl group having 2-6 carbon atoms substituted with an alkoxy group having 1-4 carbon atoms, each of R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently is hydrogen, a halogen, an alkyl group having 1-6 carbon atoms, an alkoxy group having 1-6 carbon atoms, a fluorine-substituted alkyl group having 1-6 carbon atoms, or a fluorine-substituted alkoxy group having 1-6 carbon atoms. The new imidazole derivatives are effective particularly as anti-ulcer agents.
REFERENCES:
Okabe et al., "Preparation and Formulation, Etc." CA 113:97602k (1990).
Honma et al., "Preparation of 1-(Pyridyl or, etc.)" CA 109:211050y (1988).
Masaki Mitsuo
Matsukura Hitoshi
Nomura Yutaka
Okabe Susumu
Yamakawa Tomio
Morris Patricia L.
Nippon Chemiphar Co., Ltd.
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