Sulfinic acid adducts of organo nitroso compounds useful as retr

Details Sulfinic acid adducts of organo nitroso compounds useful as retr Sulfinic acid adducts of organo nitroso compounds useful as retr

1992-10-30

1993-11-16

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

564 98, 564 99, C07C31131, A61K 31095

Patent

active

052625648

ABSTRACT:
The subject invention provides for novel anti-tumor and anti-retroviral compounds. More specifically, the invention relates to the sulfinic acid adducts of therapeutic C-nitroso compounds. The formation of the adducts increases the stability and more solubility of the C-nitroso compounds. These compounds include the L-cysteinesulfinic acid adducts of 6-nitroso-1,2-benzopyrone and 3-nitrosobenzamide. The invention also provides for compositions containing one or more of the compounds, and for methods of treating retroviral infections, cancer, infectious virus concentration with the subject compounds and compositions.

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