Sulfated homopolysaccharides as anti-AIDS virus agents

Details Sulfated homopolysaccharides as anti-AIDS virus agents Sulfated homopolysaccharides as anti-AIDS virus agents

1989-05-10

1991-10-01

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536122, A61K 31715, C08B 3700

Patent

active

050533983

ABSTRACT:
An anti-AIDS virus agent comprising a sulfate of a polysaccharide having repeating units of the formula: ##STR1## and having a molecular weight of at most 1,000,000 (n.ltoreq.1544).

REFERENCES:
patent: 4590181 (1986-05-01), McCarthy
patent: 4783446 (1988-11-01), Neushul
patent: 4840941 (1989-06-01), Ueno et al.
patent: 4948881 (1990-08-01), Naggi et al.
Ehresmann et al., Marine algae in Pharmaceutical Science, Eds. H. A. Hoppe, T. Levring, Y. Tanaka, pp. 293-302 (1979), Walter de Gruyter, NY.
Ito et al., Eur. J. Clin. Microbiol. Infect. Dis., 8:171-173 (1989).
Sugawara et al., Experientia 45:996-998 (1989).
Ito et al., Antiviral Research, 7:361-367 (Jun. 1987).
Yoshida et al., Biochemical Pharmacology, 37(15):2887-2891 (Aug. 1988).
Bagasra et al., Journal of Infectious Diseases, 158(5):1084-1087 (Nov. 1988).
Agric. Biol. Chem., vol. 45, No. 2, 1981, pp. 525-526, Y. Iwamuro et al., "Structural Analysis of an Extracellular Polysaccharide of Porodisculus Pendulus".
Jpn. J. Exp. Med., vol. 58, No. 3, Jun. 1988, pp. 145-151, K. Mizumoto et al., "Sulfated Homopolysaccharides with Immunomodulating Activities are More Potent Anti-HTLV-III Agents than Sulfated Heteropolysaccharides".
Gann, vol. 60, Apr. 1969, pp. 137-144, N. Komatsu et al., "Host-mediated Antitumor Action of Schizophyllan, a Glucan Produced by Schizophyllum Commune".
Jpn. J. Cancer Res. (Gann), vol. 78, Nov. 1987, pp. 1164-1168, H. Nakashima et al., "Sulfation of Polysaccharides Generates Potent and Selective Inhibitors of Human Immunodeficiency Virus Infection and Replication in Vitro".
Agric. Biol. Chem., vol. 50, No. 6, 1986, p. 1635, T. Kojima et al., "Biological Activity of Sulfated Schizophyllan".
Antimicrobial Agents and Chemotherapy, vol. 31, No. 10, Oct. 1987, pp. 1524-1528, American Society for Microbiology, US, H. Nakashima et al., "Purification and Characterization of an Avian Myeloblastosis and Human Immunodeficiency Virus Reverse Transcriptase Inhibitor, Sulfated Polysaccharides extracted from Sea Algae".

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