Sulfated glycosaminoglycanoid derivatives of the heparin sulfate

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 21, 536 53, 536119, 536122, 536124, C07H 1100, C07H 1302, C07H 100

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active

057736057

ABSTRACT:
The invention relates to sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type, of which N-sulfate, N-acetate, and hydroxy groups, are replaced by alkoxy, aryloxy, aralkoxy, or O-sulfate groups. The compounds have antithrombotic and smooth muscle cell proliferation inhibiting activities.

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patent: 4841041 (1989-06-01), van Boeckel et al.
patent: 5380716 (1995-01-01), Conrad et al.

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