Sulfated glycosaminoglycanoid derivatives of the heparin and hep

Details Sulfated glycosaminoglycanoid derivatives of the heparin and hep Sulfated glycosaminoglycanoid derivatives of the heparin and hep

1992-07-27

1995-01-03

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536120, 536122, 5361231, C07H 1100, A61K 31715

Patent

active

053788290

ABSTRACT:
The invention relates to sulfated glycosaminoglycanoid derivatives of the heparin and heparin sulfate type, of which N-sulfate, N-acetate, and hydroxy groups, are replaced by alkoxy, aryloxy, aralkoxy, or O-sulfate groups. The compounds have antithrombotic and smooth muscle cell proliferation inhibiting activities.

REFERENCES:
patent: 3301848 (1967-01-01), Halleck
patent: 4818816 (1989-04-01), Petitou et al.
patent: 4841041 (1989-06-01), Van Boeckel et al.

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