Sulfanyl derivatives and their use as synthesis intermediates

Details Sulfanyl derivatives and their use as synthesis intermediates Sulfanyl derivatives and their use as synthesis intermediates

2008-07-17

2011-12-27

Sullivan, Peter O (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfonic acids or salts thereof

Reexamination Certificate

active

08084638

ABSTRACT:
The present application relates to sulfanyl derivatives of formula (I) and to their use as synthesis intermediates, especially for the preparation of the pharmaceutically active compound mesna. Formula (I), wherein X is O or N—C(NH)NH2; M+ is hydrogen, sodium, disodium, potassium, dipotassium, ammonium (NH4)+, diammonium, quaternary ammonium, calcium or magnesium.

REFERENCES:
patent: 2695310 (1954-11-01), Schramm et al.
patent: WO 98/14426 (1998-04-01), None
patent: WO 02/06216 (2002-01-01), None
patent: WO 2005/058005 (2005-06-01), None
Schramm C. H. et al.: “The synthesis of mercaptoalkanesulfonic acids,” J. Am. Chem. Soc., vol. 77, No. 23, 1955, pp. 6231-6233.
Jary, Jiri et al.: “Method of 2-Mercaptoethane Sulfonic Acid Production,” CAPLUS, Feb. 12, 1987.
Schramm, C. H. et al.: “The synthesis of mercaptoalkanesulfonic acids,” J. Am. Chem. Soc., vol. 77, No. 23, 1955, pp. 6231-6233.

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