Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-06-18
1976-04-13
Roberts, Elbert L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602948G, 2602948R, 2603068R, 260309, 2603322A, 2603472, 260470, 26050112, 260516, 260519, 424263, 424270, 424273, 424275, 424285, 424304, 424310, 424316, 424319, C07C14378
Patent
active
039503763
ABSTRACT:
Compounds of the general formula ##SPC1##
In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R.sub.2 stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, hydroxy, or lower alkoxy; X and Y stand for oxygen or sulphur; their salts and esters and methods for their preparation.
The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.
REFERENCES:
patent: 3634583 (1972-01-01), Feit
patent: 3706790 (1972-12-01), Sprague et al.
patent: 3806534 (1974-04-01), Feit
Bruun Herta
Feit Peter Werner
Nielsen Ole Bent Tvaermose
Leo Pharmaceutical Products Ltd. A/S
Roberts Elbert L.
Torrence Dolph H.
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