Sulfamylbenzoic acid derivatives

Details Sulfamylbenzoic acid derivatives Sulfamylbenzoic acid derivatives

1975-02-19

1977-04-19

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260290HL, 2602948E, 260295AM, 260297R, 260302F, 260304R, 260329S, 2603323R, 2603325, 2603472, 2603473, 2603478, 260515R, 260515A, 260515M, 424232, 424270, 424275, 424285, C07D33324

Patent

active

040187942

ABSTRACT:
Compounds of the general formulae ##STR1## in which R.sub.1 represents a straight or branched, optionally substituted alkyl, alkenyl or alkynyl radical; R.sub.2 stands for an optionally substituted phenyl radical; Y stands for oxygen, sulphur or a methylene radical; X stands for O or H.sub.2 ; their salts and esters and methods for their preparation.
The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.

REFERENCES:
feit, "Journal of Medicinal Chem", (1974), vol. 17, No. 6, pp. 572-578.

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