Sulfalation of tetraol

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

active

06180799

ABSTRACT:

RELATED APPLICATIONS
None
STATEMENT OF GOVERNMENT INTEREST
The invention described herein may be manufactured and used by or for the Government for governmental purposes without the payment of any royalty thereon.
FIELD OF THE INVENTION
This invention relates to methods of preparing disulfites and disulfates particularly pentaerythritol disulfite and disulfate.
BACKGROUND OF THE INVENTION
The literature methodology for pentaerythritol disulfite requires thionyl chloride as a reagent and as a reaction media or solvent. This means excessive use of thionyl chloride that is corrosive, expensive and lachrymose. Such prior art method thus suffers problems in handling of thionyl chloride, scale-up and cost.
As for pentaerythritol disulfate it has been reported in the literature in a low yield (17%) but no procedure is given in an Article by H. Gulyas et al in J. Chem. Soc. Chem. Comm., 1997, 2385.
Accordingly there is need and market for preparation of the above compounds that overcomes the above prior art shortcomings.
There has now been discovered a method for preparation of the above compounds that avoids excessive use of thionyl chloride with improved handling and at reduced cost.
SUMMARY OF THE INVENTION
Broadly, the present invention provides an inventive method for preparing pentaerythritol disulfite (2) from pentaerythritol (1) and an inventive method for preparing pentaerythritol disulfate (3) from 2, according to the following reaction scheme.
The invention will become more apparent from the following detailed specification given below.


REFERENCES:
patent: 2471274 (1949-05-01), Lingo
patent: 2587641 (1952-04-01), Moersch et al.
patent: 4924007 (1990-05-01), Massonneau et al.
patent: 5116999 (1992-05-01), Le Roy et al.

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