Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical
Patent
1988-03-31
1989-08-15
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Food or edible as carrier for pharmaceutical
424439, 424441, 424484, 424485, 424488, 426517, A61K 968
Patent
active
048573310
ABSTRACT:
A sugarless ingestible gel confectionary delivery system which includes a pectin gel component, an algin gel component and a polymer network gel component in amounts sufficient to form a gel confectionery unit. The inventive gel confectionery unit has reduced intrinsic viscosity prior to gelation which permits the inclusion of an edible insoluble solid in an amount sufficient to strengthen the internal combination pectin-algin gel network and to bind internal moisture sufficiently to enhance mold removal capabilities. The delivery system also includes hydrogenated starch hydrolysates. The delivery system may also include a further active ingredient such as a drug, medicament, or nutritional supplement. The product and method of the present invention also includes a composition in which the gel delivery system can be molded directly in the receptacle which is used to dispense the confectionery unit to the consumer.
REFERENCES:
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patent: 4551331 (1985-11-01), Rudin
patent: 4565702 (1986-01-01), Morley et al.
patent: 4689229 (1987-08-01), Banik
patent: 4766004 (1988-08-01), Moskowitz
Hawley's Condensed Chemical Dictionary, eleventh ed., selected sections (1987).
Kelco, "Algin/Hydrophilic Derivatives of Alginic Acid for Scientific Water Control", second ed., p. 6-8.
Remington's Pharmaceutical Sciences, fifteenth ed., selected sections (1975).
Sprowls' American Pharmacy, seventh ed., selected sections (1974).
Toft, K., "Interactions Between Pectins and Alginates", Prop. Pd., Nutr. Sci., vol. 6, pp. 89-96 (1982).
Bunick Frank J.
Shaw James J.
Field Sandra G.
Page Thurman K.
Prater Penny
Warner-Lambert & Company
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