Sugar kinase

Details Sugar kinase Sugar kinase

1999-06-29

2000-12-26

Achutamurthy, Ponnathapu

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Transferases

435194, 4352523, 4353201, 435 691, 435883, 530300, 530350, 536 232, 536 237, A61K 3851, C12N 912, C12N 120, C12N 1500, C07H 2104

Patent

active

061654620

ABSTRACT:
The invention provides sugar kinase polypeptides and DNA (RNA) encoding sugar kunase polypepties and methods for producing such polypeptides by recombinant techniques. Also provided are methods or utlizng sugar kinase polypeptides to screen for antibacterial compounds.

REFERENCES:
Hope, et al., GenBank Submission, Accession No. P05054, Robokinase (EC 2.7.1.15), Aug. 13, 1987.
Hope, et al., "Robokinase from Escherichia coli K12: Nucleotide Sequence and Overexpression of the rbsK Gene and Purification of Ribokinase", Journal of Biological Chemistry, vol. 261, No. 17, pp. 7663-7668, (1986).
Titgemeyer F., et al., "Evolutionary Relationships Between Sugar Kinases and Transcriptional Repressors in Bacteria", Microbiology, vol. 140, No. 9, pp. 2349-2354, Sep. 1994.
Bork P, et al., "An ATPase Domain Common to Prokaryotic Cell Cycle Proteins, Sugar Kinases, Actin and hsp70 Heat Shock Proteins", Proceedings of the National Academy of Sciences of the USA, vol. 89, pp. 7290-7294, Aug. 1992.
European Search Report, completed Sep. 24, 1999, from corresponding European Application No. 97307424.8, filed Sep. 23, 1997.

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