Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-05-26
2011-11-29
Garcia, Marcela M Cordero (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C436S086000, C536S123130
Reexamination Certificate
active
08067393
ABSTRACT:
It is intended to provide a stable novel sugar-immobilized metal nanoparticle capable of easily immobilizing a sugar chain, a method for measuring sugar-protein interaction easily and at a low cost using the same without labeling, and a method for simply recovering a protein from a sugar-protein interactant. A maltose-immobilized gold nanoparticle was obtained by binding a ligand complex, in which maltose and a linker compound had been bound to each other, to a gold nanoparticle. By adding this maltose-immobilized gold nanoparticle to a dilution series of concanavalin A, a sugar-protein interactant of maltose and ConA was formed, and red-purple color derived from a colloidal solution of maltose-immobilized gold nanoparticle disappeared. That is, sugar-protein interaction could be confirmed by visual observation without labeling.
REFERENCES:
patent: 7320867 (2008-01-01), Suda et al.
patent: 2008/0145838 (2008-06-01), Suda et al.
patent: 2009/0060839 (2009-03-01), Boyes et al.
patent: 1538156 (2005-06-01), None
patent: 2004-157108 (2004-06-01), None
patent: 2004-194669 (2004-07-01), None
patent: 2004-333232 (2004-11-01), None
patent: 2005-069955 (2005-03-01), None
patent: 2006-112980 (2006-04-01), None
patent: WO-2004/022583 (2004-03-01), None
De La Fuente, J. M. et al. (2004). “Understanding Carbohydrate-Carbohydrate Interactions by Means of Glyconanotechnology,”Glycoconjugate Journal21:149-163.
Sihelnikova, L. et al. (2007). “Step by Step Towards Understanding Gold Glyconanoparticles as Elements of the Nanoworld,”Chemical Papers61(4):237-255.
Supplementary European Search Report mailed Feb. 3, 2009, for EP Application No. 06746921.3 filed May 26, 2006, 9 pages.
Takae, S. et al. (2005). “Ligand Density Effect on Biorecognition by PEGylated Gold Nanoparticles: Regulated Interaction of RCA120 Lectin with Lactose Installed to the Distal End of Tethered PEG Strands on Gold Surface,”Biomacromolecules6(2):818-824.
Zhang, J. et al. (2004). “Complexation of Polysaccharide and Monosaccharide with Thiolate Boronic Acid Capped on Silver Nanoparticle,”Analytical Biochemistry332:253-260.
Brust, M. et al. (1994). “Synthesis of Thiol-Derivatised Gold Nanoparticles in a Two Phase Liquid-Liquid System,”Journal of the Chemical Society, Chemical Communications, pp. 801-802.
CMC Technical Library 146. (Aug. 31, 1990).Development and Evaluation of Bio Diagnostic Agents, and Companies Thereof. First Edition, CMC Publishing Co., Ltd., pp. 92-97, 108-113. (partial English translation attached, 4 pages).
De La Fuente, J. M. et al. (2001). “Gold Glyconanoparticles as Water-Soluble Polyvalent Models to Study Carbohydrate Interactions,”Angewandte Chemie International Edition40(12): 2258-2261.
Feizi, T. et al. (2003). “Carbohydrate Microarrays—A New Set of Technologies at the Frontiers of Glycomics,”Current Opinion in Structural Biology13:637-645.
International Search Report mailed Jun. 27, 2006, for PCT Application No. PCT/JP2006/310592 filed May 26, 2006, 3 pages.
Otsuka, H. et al. (2001). “Quantitative and Reversible Lectin-Induced Association of Gold Nanoparticles Modified with Alpha-Lactosyl-Omega-Mercapto-Poly(Ethylene Glycol),”Journal of the American Chemical Society123:8226-8230.
Schwarz, M. et al. (2003). “A New Kind of Carbohydrate Array, its Use for Profiling Antiglycan Antibodies, and the Discovery of a Novel Human Cellulose-Binding Antibody,”Glycobiology13(11):749-754.
Stoll, M. S. et al. (2000). “Fluorescent Neoglycolipids: Improved Probes for Oligosaccharide Ligand Discovery,”European Journal of Biochemistry267:1795-1804.
Kishimoto Yuko
Nakagawa Hiromi
Nishimura Tomoaki
Suda Yasuo
Cordero Garcia Marcela M
Japan Science and Technology Agency
Morrison & Foerster / LLP
National University Corporation Kagoshima University
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