Sugar compounds for inhibition of the biosynthesis of sugar chai

Details Sugar compounds for inhibition of the biosynthesis of sugar chai Sugar compounds for inhibition of the biosynthesis of sugar chai

1993-03-02

1995-08-15

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 25, 514 53, 514 54, 514 62, 530300, 530322, 530350, 530367, 530386, 530395, 536 172, 536 175, 536 187, 536 53, 536 54, 536 552, 536 63, 536 66, 536 84, 536 92, 53612313, A61K 3170, A61K 31715, A61K 3172, A61K 3173

Patent

active

054419328

ABSTRACT:
An inhibitor of the biosynthesis of sugar chains containing sialic acid that is excellent in the suppression of inflammation or allergy, which comprises as an active ingredient a sugar compound of the formula (1): ##STR1## wherein R.sup.1 is a hydrogen atom, a substituted or unsubstituted aliphatic hydrocarbon group, a substituted or unsubstituted aromatic hydrocarbon group, a peptide residue or a glycoprotein, and R.sup.2 is a hydrogen atom, a sulfhydryl group, an acyloxy group, an acylthio group, an aryloxy group, an alkyloxy group or a glycothio residue. The inhibitor of the biosynthesis of sugar chains containing sialic acid may be used as a therapeutic agent for inflammation caused by sugar chains containing sialic acid.

REFERENCES:
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