Sugar chain

Details Sugar chain Sugar chain

1990-09-25

1992-07-21

Nutter, Nathan M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 41, C07H 100, C08B 3700

Patent

active

051324130

ABSTRACT:
A sugar chain of the following formula is disclosed. ##STR1## It can be prepared by separating glycoproteins from cell membrane components by using lectins which recognize the sugar chain, releasing the sugar chain structure from the glycoproteins, and purifying the released sugar chain. The sugar chain is useful for the diagnosis and treatment of cancer.

REFERENCES:
patent: 4849510 (1989-07-01), Adachi
patent: 4851517 (1989-07-01), Feder et al.
Shimoda et al., J. Biochem., vol. 102 (1987), pp. 657-664.
Lloyd et al., Immunogenetics, vol. 17 (1983), pp. 537-541.
Hakomori et al., Biochem. Biophys. Res. Comm., vol. 113 (1983), pp. 791-798.
Brown et al., Bioscience Reports, vol. 3 (1983), pp. 163-170.
McKibbin et al., J. Biol. Chem., vol. 257 (1982), pp. 775-760.

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