Sucralfate aqueous suspension and its method of preparation

Details Sucralfate aqueous suspension and its method of preparation Sucralfate aqueous suspension and its method of preparation

1995-04-26

1996-10-08

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536121, 536122, 536124, C07H 1100, C07H 100, A61K 31715

Patent

active

055632580

ABSTRACT:
This specification discloses a production process for an sucralfate aqueous suspension stock, the process being characterized by direct dispersement of an sucralfate aqueous stock for sucralfate preparations, which contains sucralfate particles with an average particle size of no more than 50 .mu.m in a concentration of 1-2 g/ml, in water or other aqueous medium without drying the synthesized sucralfate wet powder, followed by milling of the sucralfate particles to an average particle size of no more than 50 .mu.m. When the sucralfate aqueous suspension stock obtained directly from wet powder in accordance with this method is compared to the conventional suspension obtained from dry powder, equivalency of both stocks are obtained in terms of both properties and pharmacological activities. In comparison to the conventional process using dry powder, this wet milling method of production is economically and operationally superior and environmental pollution arising from the conventional process can be prevented.

REFERENCES:
patent: 3432489 (1969-03-01), Nitta et al.
patent: 4650888 (1987-03-01), Ochi et al.
patent: 4668665 (1987-05-01), Ishihara et al.
patent: 4885281 (1989-12-01), Hanstein et al.
patent: 4990610 (1991-02-01), Lazaridis et al.
patent: 5084446 (1992-01-01), Baldoni et al.

Affiliated with

Also associated with

Rating

Sucralfate aqueous suspension and its method of preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sucralfate aqueous suspension and its method of preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sucralfate aqueous suspension and its method of preparation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-58370