Succinoylamino hydroxyethylamino sulfonamides useful as...

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C564S093000, C544S110000, C549S075000, C514S237800, C514S438000, C514S562000, C514S603000

Reexamination Certificate

active

07038084

ABSTRACT:
Succinoylamino hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

REFERENCES:
patent: 4450164 (1984-05-01), Bristol et al.
patent: 4477441 (1984-10-01), Boger et al.
patent: 4514391 (1985-04-01), Gordon et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4599198 (1986-07-01), Hoover
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4629724 (1986-12-01), Ryono et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4668770 (1987-05-01), Boger et al.
patent: 4757050 (1988-07-01), Natarajan et al.
patent: 4839357 (1989-06-01), Patchett et al.
patent: 4880938 (1989-11-01), Freidinger
patent: H725 (1990-01-01), Gordon
patent: 4963530 (1990-10-01), Hemmi et al.
patent: 4977277 (1990-12-01), Rosenberg et al.
patent: 5081284 (1992-01-01), Higuchi et al.
patent: 5142056 (1992-08-01), Kempe et al.
patent: 5157041 (1992-10-01), Handa et al.
patent: 5194608 (1993-03-01), Toyoda et al.
patent: 5278148 (1994-01-01), Branca et al.
patent: 5463104 (1995-10-01), Vazquez et al.
patent: 5508294 (1996-04-01), Vazquez et al.
patent: 5714605 (1998-02-01), Vazquez et al.
patent: 5753660 (1998-05-01), Sikorski et al.
patent: 5760076 (1998-06-01), Vazquez et al.
patent: 6022994 (2000-02-01), Vazquez et al.
patent: 6313345 (2001-11-01), Vazquez et al.
patent: 6469207 (2002-10-01), Vazquez et al.
patent: 6727282 (2004-04-01), Vazquez et al.
patent: 104041 (1984-03-01), None
patent: 114993 (1984-08-01), None
patent: 172347 (1986-02-01), None
patent: 223437 (1987-05-01), None
patent: 0 264 795 (1988-04-01), None
patent: 337714 (1989-10-01), None
patent: 0 342 541 (1989-11-01), None
patent: 0 346 847 (1989-12-01), None
patent: 356223 (1990-02-01), None
patent: 389898 (1990-10-01), None
patent: 393445 (1990-10-01), None
patent: 393457 (1990-10-01), None
patent: 402646 (1990-12-01), None
patent: 468641 (1992-01-01), None
patent: 2184730 (1987-07-01), None
patent: 2200115 (1988-07-01), None
patent: 2209752 (1989-05-01), None
patent: WO84/03044 (1984-08-01), None
patent: WO 92/00750 (1992-01-01), None
patent: WO92/08699 (1992-05-01), None
Collier, A., et al., “Treatment of Human Immunodeficiency Virus Infection with Saquinavir, Zidovudine, and Zalcitabine,” N. Engl. J. Med., vol. 334(16), pp. 1011-1017 (Apr. 18, 1996), at p. 1015, lines 33-35.
Collier, A., et al., “Treatment of Human Immunodeficiency Virus Infection with Saquinavir, Ziodvudine, and Zalcitabine,” N. Engl. J. Med., vol. 334(16), pp. 1011-1017 (Apr. 1996), at p. 1015, lines 33-35.
Leung, S., and Grant, D., “Solid State Stability Studies of Model Dipeptides: Aspartame and Aspartylphenylalanine,” J. Pharm. Sci., vol. 86(1), pp. 64-71 (Jan. 1997), at p. 65, Scheme 1.
Su, T., et al., “Fibrinogen Receptor (GPllb-llla) Antagonists Derived from 5,6-Bicyclic Templates,” J. Med. Chem., vol. 40(26), pp. 4308-4318 (Dec. 1997), at p. 4313, col. 2, Table 7, and lines 20-29 and 40-44 (alpha—sulfonamide derivatives).
Rosenberg et al,J. Med. Chem., 30, 1224-1228 (1987).
Roberts et al, “Rational Design of Peptide-based Proteinase Inhibitors,”Science, 248, 358 (1990).
Erickson et al, “Design Activity, and 2.8A Crystal Structure of a C2Symmetric Inhibitor Complexed to HIV-1 Protease,” Science, 249, 527 (1990).
Pearl et al, “Sequence specificity of retroviral proteases”Nature, 328, (1987) vol. 328, 482 (Aug. 6, 1987).
Martin,Drugs of the Future, 16(3), 210-212 (1991).
Meek et al.Letter To Nature, 343, 90-92 (1990).
McQuade et al.Science, 247, 454-456, “A Synthetic HIV-1 Protease Inhibitor,” (Jan. 26, 1990).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Succinoylamino hydroxyethylamino sulfonamides useful as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Succinoylamino hydroxyethylamino sulfonamides useful as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Succinoylamino hydroxyethylamino sulfonamides useful as... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3607624

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.