Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1997-03-20
1998-10-27
Hendricks, Keith D.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
435189, 4353201, 435325, 4352523, 43525233, 43525411, 4352542, 435419, 536 232, 536 2431, C12N 121, C12N 1563, C12N 902
Patent
active
058277110
ABSTRACT:
The present invention provides a human succinate-ubiquinone reductase membrane anchor subunit (SDHMA) and polynucleotides which encode SDHMA. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of SDHMA.
REFERENCES:
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Yu, L., et al., "Cytochrome b.sub.560 (QPs1) of Mitochondrial Succinate-Ubiquinone Reductase", The Journal of Biological Chemistry, 267 (34): 24508-24515 (1992).
Birch-Machin, M.A., et al., "The Sequence of the Flavoprotein Subunit of Bovine Heart Succinate Dehydrogenase", The Journal of Biological Chemistry, 267(16): 11553-11558 (1992).
Shenoy, S.K., et al., (GI 1575011) GenBank Sequence Database (Accession U50987), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. Date Not Available.
Shenoy, S.K., et al., (GI 1575010) GenBank Sequence Database (Accession U50987), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. Date Not Available.
Cochran, B., et al., (GI 1705529) GenBank Sequence Database (Accession P35720), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. Date Not Available.
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Lal Preeti
Shah Purvi
Billings Lucy J.
Hendricks Keith D.
Incyte Pharmaceuticals Inc.
Mayhew Bradley S.
Mohan-Peterson Sheela
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