Subunit canine parvovirus vaccine

Drug – bio-affecting and body treating compositions – Lymphokine

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424 89, A61K 39175

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active

049717936

ABSTRACT:
A recombinant subunit vaccine for protecting dogs against infection caused by canine parvovirus comprising VP-2 protein produced during replication of a recombinant baculovirus in insect tissue culture cells or insects which are a permissive host for the replication of selected baculoviruses.

REFERENCES:
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patent: 4303645 (1981-12-01), Carmichael et al.
Parrish et al., Antigenic Relationships Between Canine Parvovirus Type-2, Feline Panleukopenia Virus . . . 1982 Archives of Virology 72, pp. 267-278.
Parrish et al., Antigenic Structure and Variation of Canine Parvovirus Type -2, Feline Panleukopenia Virus, . . . 1983 Virology 129, pp. 401-414.
Luckow et al., Trends in the Development of Baculovirus Expression Vectors 1988 Bio/Technology 6, pp. 47-55.
G. Smith et al., Molecular & Cellular Biology v3 (12) pp. 2156-2165, Dec. 1983
S. Halling et al., Chemical Abstracts v101 (25) 224015a, Dec. 17, 1984.
G. P. Mazzara et al., In "Vaccines, 87: Modern Approaches to New Vaccines: Prevention of AIDS & Other Viral, Bacterial & Parasitic Diseases", pp. 419-424, 9-1987/1986 Meeting.

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