Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1990-10-19
1993-02-09
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435219, 435221, 435222, 4353201, 435243, 4352523, 4352401, 4351723, 935 10, 935 14, 935 66, 536 232, C12N 952, C12N 954, C12N 1557, C07H 2104
Patent
active
051852586
ABSTRACT:
Novel carbonyl hydrolase mutants derived from the DNA sequences of naturally-occurring or recombinant non-human carbonyl hydrolases are disclosed. The mutant carbonyl hydrolases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant carbonyl hydrolase to generate the substitution of one or more amino acid residues in the amino acid sequence of a precursor carbonyl hydrolase. Such mutant carbonyl hydrolases have properties which are different from those of the precursor hydrolase and are especially useful in detergent formulations. The substituted amino acid residues correspond to position +123 and/or +274 in Bacillus amyloliquefaciens subtilisin.
REFERENCES:
patent: 4914031 (1990-04-01), Zukowski et al.
Meloun, B. et al. (1985) Febs. Letters 183:195-200.
Caldwell Robert M.
Estell David A.
Graycar Thomas P.
Bugaisky Gabriele E.
Genencor International Inc.
Horn Margaret A.
Wax Robert A.
LandOfFree
Subtilisin mutants does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Subtilisin mutants, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Subtilisin mutants will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-325077