Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2002-08-26
2010-02-23
Lam, Ann Y (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S288300, C435S288400
Reexamination Certificate
active
07666661
ABSTRACT:
The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assasy format.
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Gupta et al., “Optical Amplification of Ligand-Receptor Binding Using Liquid Crystals”, Science, vol. 279, Mar. 1998, pp. 2077-2080.
Green et al., “Mechanism of the Transformation of a Stiff Polymer Lyotropic Nematic Liquid Crystal to the Cholesteric State by Dopant-Mediated Chiral Information Transfer”, J. Am. Chem. Soc., 1998, 120, 9810-9817.
Abbott Nicholas
Israel Barbara
Murphy Christopher
Casimir Jones S.C.
Lam Ann Y
Platypus Technologies, LLC
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