Combinatorial chemistry technology: method – library – apparatus – Method of screening a library – By measuring the ability to specifically bind a target...
Reexamination Certificate
2000-09-14
2008-08-19
Epperson, Jon D (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Method of screening a library
By measuring the ability to specifically bind a target...
C506S011000, C506S012000
Reexamination Certificate
active
07413536
ABSTRACT:
A variety of methods for assaying libraries of test compounds as ligands and/or substrates of transport proteins, including both carrier-type and receptor-type transport proteins, are provided. Both in vitro and in vivo screening methods are disclosed. Also provided are methods for screening DNA libraries to identify members that encode transport proteins. Pharmaceutical compositions including compounds identified via the screening methods are also provided.
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Barrett Ronald W.
Chernov-Rogan Tania
Cundy Kenneth C.
Dower William J.
Gallop Mark A.
Epperson Jon D
Townsend and Townsend / and Crew LLP
XenoPort, Inc.
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