Substrate material for simultaneously binding genotypic and phen

Details Substrate material for simultaneously binding genotypic and phen Substrate material for simultaneously binding genotypic and phen

1997-04-10

1998-12-15

Houtteman, Scott W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 915, 435 5, 536 243, C12P 1934

Patent

active

058495452

ABSTRACT:
Described is a support material that can simultaneously bind both genotypic and phenotypic substances. The respective areas, which can have surface-modifying matter such as anionic exchangers and/or affinity ligands, simultaneously bind, for example, nucleic acids and proteins or peptides. The support materials described can be used in processes for evolutive optimization of biopolymers, wherein genotype and phenotype can be bound at the same time so as to furnish them for further analysis.

REFERENCES:
patent: 4379843 (1983-04-01), Cashion
patent: 4873192 (1989-10-01), Kunkel
patent: 5143854 (1992-09-01), Pirrung et al.
Berichte Der Bunsen-Gesellschaft Fur Physikalische Chemie vol. 89, No. 6, Jun. 1985, pp. 658-667; "Macromolecular Evolution: Dynamical Ordering in Sequence Space".
Abstract of Hunger et al patent DD-274676, (1990).

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