Substrate for liquid chromatography and process for isolating an

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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2105021, B01A 1508

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active

044977107

ABSTRACT:
A substrate for liquid chromatography comprising a spherical particle of highly cross-linked polymer which is produced from (a) 100 parts by weight of a monomer of vinyl ester, acrylate or methacrylate, these esters having a long alkyl chain, if desired, together with a comonomer copolymerizable with the monomer and (b) 10 to 80 parts by weight of a cross-linking agent copolymerizable with the monomer and having at least two functional groups, and a process for isolating and purifying a fat-soluble substance, for instance, a lower alkyl ester of eicosapentaenoic acid or docosahexaenoic acid by means of the liquid chromatography on the substrate.

REFERENCES:
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patent: 3586626 (1971-06-01), Heitz
patent: 3657117 (1972-04-01), Pfitzneh et al.
patent: 4046720 (1977-09-01), Rembaum et al.
patent: 4128706 (1978-12-01), Seita et al.
patent: 4314032 (1982-02-01), Muhayama et al.
patent: 4338404 (1982-07-01), Tanaka et al.
Chromatographic and Allied Methods by Mikes, John Wiley & Sons of New York, pp. 212-214, 1979.
Bulletin of the Japanese Society of Scientific Fisheries "Preparation of Eicosapentaenoic and Docosahexaenoic Acids by Reversed Phase High Performance Liquid Chromatography", 47(5), 675, 1981.
Bulletin of the Jap. Society of Scientific Fisheries, "Separation of Polyunsaturated Fatty Acids by Column Chromatography on a Silver Nitrate-Impregnated Silica Gel", 44(8), 927, 1978.
Patent Abstracts of Japan, vol. 5, No., 62, Apr. 25, 1981, "Gel for Filtration".

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