Substrate assisted catalysis

Details Substrate assisted catalysis Substrate assisted catalysis

1994-09-22

1995-12-05

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435222, 435221, C12P 2106, C12N 956

Patent

active

054728550

ABSTRACT:
Novel enzyme mutants are disclosed which are derived from a precursor enzyme by replacing or modifying at least one catalytic functional group of an amino acid residue in a precursor enzyme. Such mutant enzymes have a catalytic preference for substrates which provide the replaced or modified catalytic group or its equivalent such that the substrate together with the enzyme mutant assists in its own catalysis.

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