Substrate assisted catalysis

Details Substrate assisted catalysis Substrate assisted catalysis

1995-06-07

1997-07-29

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 435222, 435221, 536 234, C12N 1563, C12N 1531

Patent

active

056521367

ABSTRACT:
Novel enzyme mutants are disclosed which are derived from a precursor enzyme by replacing or modifying at least one catalytic functional group of an amino acid residue in a precursor enzyme. Such mutant enzymes have a catalytic preference for substrates which provide the replaced or modified catalytic group or its equivalent such that the substrate together with the enzyme mutant assists in its own catalysis.

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