Substrate assisted catalysis

Details Substrate assisted catalysis Substrate assisted catalysis

1993-07-12

1994-12-06

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435221, 530350, C12N 956, C12N 954

Patent

active

053710088

ABSTRACT:
Novel enzyme mutants are disclosed which are derived from a precursor enzyme by replacing or modifying at least one catalytic functional group of an amino acid residue in a precursor enzyme. Such mutant enzymes have a catalytic preference for substrates which provide the replaced or modified catalytic group or its equivalent such that the substrate together with the enzyme mutant assists in its own catalysis.

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