Substitution fluid preparation comprising 3-hydroxy-butyric acid

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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A61K 3119

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active

052927741

ABSTRACT:
The present invention provides a substitution fluid preparation which is characterized by containing at least one selected from 3-hydroxybutyric acid, 3-sodium hydroxybutyrate and 3-potassium hydroxybutyrate. The substitution fluid preparation of the present invention can be easily metabolized in the body of a patient to provide a good energy source and is also effective for suppressing increased protein catabolism in the living body.

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patent: 5100677 (1992-03-01), Veech
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The Journal of Clinical Investigation, vol. 55, No. 6, Jun. 1975, pp. 1382-1390, The American Society of Clinical Investigation, Inc.; R. S. Sherwin et al. "Effect of ketone infusions on amino acid and nitrogen metabolism in man".
Pawan, G. et al., "Effect of 3-Hydroxybutyrate in Obese Subjects on Very-Low-Energy and During Therapeutic Starvation", The Lancet Jan. (1983) pp. 15-17.
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