Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1993-04-27
1994-03-08
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A61K 3119
Patent
active
052927741
ABSTRACT:
The present invention provides a substitution fluid preparation which is characterized by containing at least one selected from 3-hydroxybutyric acid, 3-sodium hydroxybutyrate and 3-potassium hydroxybutyrate. The substitution fluid preparation of the present invention can be easily metabolized in the body of a patient to provide a good energy source and is also effective for suppressing increased protein catabolism in the living body.
REFERENCES:
patent: 4579955 (1986-04-01), Lammerant et al.
patent: 4663166 (1987-05-01), Veech
patent: 4771074 (1988-09-01), Lammerant et al.
patent: 5100677 (1992-03-01), Veech
The Journal of Nutrition, vol. 116, No. 1, Jan. 1986, pp. 149-156, The American Institute of Nutrition; A. Maiz et al. "Effect of DL-3-hydroxybutyrate infusions on leucine and glucose kinetics in burned rats receiving TPN".
Surgical Forum, vol. 39, 1988, editor M. Pannell, pp. 48-50, American College of Surgeons, Chicago, Ill., US; R. R. Jodoin et al.: "Determination of body composition from whole body electrical impedance".
The Journal of Clinical Investigation, vol. 55, No. 6, Jun. 1975, pp. 1382-1390, The American Society of Clinical Investigation, Inc.; R. S. Sherwin et al. "Effect of ketone infusions on amino acid and nitrogen metabolism in man".
Pawan, G. et al., "Effect of 3-Hydroxybutyrate in Obese Subjects on Very-Low-Energy and During Therapeutic Starvation", The Lancet Jan. (1983) pp. 15-17.
The Merck Index 10th edition cite #4727 p. 700 (1983).
Mainichi Newspaper, Nov. 18, 1987, Japanese Association for Acute Medicine, Atsushi Hiraide et al.
Journal of Japan Surgical Society, Feb. 25, 1988, Atsushi Hiraide et al.
15th Annual meeting of Japanese Association for Acute Medicine Mar. 22, 1988, Atsushi Hiraide et al.
Japanese Association of Parenteral and Enteral Nutrition proceeding, issued Dec. 1987, Atsushi Hiraide et al.
Journal of Japan Surgical Society, May 1, 1988, Atsushi Hiraide et al.
48th Annual Session of American Association for the Surgery of Trauma Abstract, Oct. 6-8, 1988, Atsushi Hiraide et al.
Hiraide Atsushi
Katayama Masami
Henley III Raymond J.
Kanegafuchi Kagaku Kogyo & Kabushiki Kaisha
Waddell Frederick E.
LandOfFree
Substitution fluid preparation comprising 3-hydroxy-butyric acid does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substitution fluid preparation comprising 3-hydroxy-butyric acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substitution fluid preparation comprising 3-hydroxy-butyric acid will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-153818