Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-06-25
1977-02-15
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602948C, 2602948H, 260295E, 260295F, 2602955D, 2602955B, A61K 31395, C07D21375
Patent
active
040083268
ABSTRACT:
A method of improving the endogenous production of prostaglandins by a mammal is disclosed, which comprises administering to the mammal an effective amount of 1-pyridylalkyl-3-naphthyl-2(thio)ureas. Disclosed also are novel substituted 1-pyridylalkyl-3-naphthyl-2(thio)ureas and therapeutic compositions thereof which are useful in carrying out the method of the invention.
Disclosed also are methods of treating mammals for clinical conditions responsive to prostaglandins, such as, for example, male infertility, epidermal injuries, atonic uterine bleeding, thromboembolic disease and like clinical conditions.
REFERENCES:
novikov et al., Chem. Abstracts, vol. 70, (1) 3776p Jan. 6, 1969.
Chem. Abstracts, Eighth Collective Index, Subjects Triplet-Z, p. 32,479S (1967-1971).
Callahan William A.
Glenn Eldridge Myles
Rector Douglas L.
Barancik Martin B.
Rotman Alan L.
Saliwanchik Roman
The Upjohn Company
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