Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-05-02
2006-05-02
Desai, Rita (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S339000, C546S080000, C546S284100
Reexamination Certificate
active
07037920
ABSTRACT:
Heterocyclic-substituted tricyclics of the formulaor a pharmaceutically acceptable salts thereof, wherein:n1and n2are independently 0-2;Het is an optionally substituted mono-, bi- or tricyclic heteroaromatic group;B is alkyl or optionally substituted alkenyl;R22is —COR23or a carboxy, sulfinyl, sulfonyl, sulfonamide or amino acid derivative;R23is haloalkyl; alkenyl; haloalkenyl; alkynyl; optionally substituted cycloalkyl; cycloalkyl-alkyl; aryl; arylalkyl; heteroaryl; heterocycloalkyl; or —COOH and/or —SO3H substituted alkyl;R1, R2, R3, R9, R10and R11are as defined in the specification;are disclosed, as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds.
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Chackalamannil Samuel
Chelliah Mariappan V.
Clasby Martin C.
Xia Yan
Desai Rita
Lee William Y.
Reinhardt Gerard E.
Schering Corporation
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