Substituted triazole compounds

Details Substituted triazole compounds Substituted triazole compounds

2007-09-11

2007-09-11

Anderson, Rebecca (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S326000, C548S255000, C546S210000

Reexamination Certificate

active

11488837

ABSTRACT:
The present invention relates to compounds of formula (I)whereinR1, R2and R3are as defined in the specification and to pharmaceutically suitable acid addition salts thereof. The invention includes all sterioisomeric forms, including individual diastereoisomers and enantiomers of the compound of formula (I) as well as racemic and non-racemic mixtures thereof. It has been found that the present compounds are selective allosteric positive modulators of the human NK-3 receptor for the treatment of anxiety, depression, bipolar disorders, Parkinson's disease, schizophrenia and pain.

REFERENCES:
patent: WO 2005/000821 (2005-01-01), None
patent: WO 2005/014575 (2005-02-01), None
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