Substituted thiopyrano(4,3-b)pyrans

Details Substituted thiopyrano(4,3-b)pyrans Substituted thiopyrano(4,3-b)pyrans

1978-04-05

1978-11-28

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

424279, 542449, A61K 31335, A61K 3138, C07D49302, C07D49702

Patent

active

041276671

ABSTRACT:
3,4,7,8-Tetahydro-2H,5H-thiopyrano[4,3-b]pyrans of the structure ##STR1## are provided wherein X is O, S or SO.sub.2, R is hydrogen, halogen, lower alkyl, lower alkoxy, cyano or trifluoromethyl, and R' is carbethoxy, carboxy, alkali metal carboxylate and cyano. These compounds are useful as antiinflammatory agents and anti-hypertensive agents.

REFERENCES:
patent: 3979381 (1976-09-01), Rovnyak
Linde et al, Chemical Abstracts, vol. 67, Abst. No. 32610y (1967).
Biglino et al, Chemical Abstracts, vol. 72, Abst. No. 100558t (1970).
Chemical Abstracts, vol. 84, Subject Index p. 5150CS (1976).
Tan et al, Chemical Abstracts, vol. 86, Abst. No. 106428m (1977).

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