Substituted thiophenesulfonylureas and -thioureas, processes for

Details Substituted thiophenesulfonylureas and -thioureas, processes for Substituted thiophenesulfonylureas and -thioureas, processes for

1996-01-30

1998-08-11

Lambkin, Deborah C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549 65, A61K 3138, C07D33332

Patent

active

057927880

ABSTRACT:
Substituted thiophenesulfonylureas and -thioureas I ##STR1## wherein R(1) is selected from the group consisting of hydrogen, halogen, alkyl having 1 or 2 carbon atoms, alkoxy having 1 or 2 carbon atoms, mercaptoalkyl having 1 or 2 carbon atoms, fluoroalkoxy having 1 or 2 carbon atoms, and fluoroalkyl having 1 or 2 carbon atoms;

REFERENCES:
patent: 3124597 (1964-03-01), Stoll et al.
patent: 3494936 (1970-02-01), Weger et al.
patent: 3998968 (1976-12-01), Hitzel et al.
patent: 5476850 (1995-12-01), Englert et al.
S. Amoroso et al., "Glucose, Sulfonylureas, and Neurotransmitter Release: Role of ATP-Sensitive K+ Channels" Science, vol. 247, (1990) pp. 852-854.
N. Sturgess et al., "The Sulphonylurea Receptor May Be A ATP-Sensitive Potassium Channel" The Lancet, vol. 2, No. 8453, (1955) pp. 474-475.
M. Fosset et al., "Identification, Mecanisms de Fonctionnement et Regulation des Canaux Potassium Sensibles A L'ATP Cibles des Sulfonylurees Utilisees Dans le Traitement du Diabete de Type II" Jorn. Annu. Diabetol. (1989) pp. 7-11.
Chemical Abstract of DE-B-1 518 874, vol. 82, p. 408, No. 43073m, 1975.

Affiliated with

Also associated with

Rating

Substituted thiophenesulfonylureas and -thioureas, processes for does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted thiophenesulfonylureas and -thioureas, processes for, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted thiophenesulfonylureas and -thioureas, processes for will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-389387