Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-11-21
2010-10-05
Chung, Susannah (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S250000
Reexamination Certificate
active
07807702
ABSTRACT:
The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.
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Kurukulasuriya, Ravi et al. “Biaryl amide glucagon receptor antagonists”Bioorganic&Medicinal Chemistry Letters, 14(9), p. 2049; table 1; 2004.
Beasley, Helen L. et al. “Development of a Panel of Immunoassays for Monitory DDT, Its Metabolites, and Analogs in Food and Environmental Matrixes”Journal of Agricultural and Food Chemistry, 46(8), pp. 3339-3352; compound Hapten VI, 1998.
Kundu, B. et al. “Identification of novel.alpha.-glucosidase inhibitors by screening libraries based on N-'r-(Benzyloxy) benzoyl! alanine derivatives”Chemical Abstratcts Service, 5(7), pp. 545-550, 2002.
Chappell Mark Donald
Conner Scott Eugene
Hipskind Philip-Arthur
Tripp Allie Edward
Zhu Guoxin
Chung Susannah
Eli Lilly and Company
Wood Dan L.
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