Substituted thienyl-acetic acid esters

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

26032635, 2603322A, 424267, 424274, 424275, C07D40912, C07D33324

Patent

active

040050955

ABSTRACT:
Substituted thienyl-acetic acid esters of the formula: ##STR1## in which R.sub.1 and R.sub.2 each, independently is H, CH.sub.3, C.sub.2 H.sub.5, C.sub.3 H.sub.7, OCH.sub.3, SCH.sub.3, Cl Br or NO.sub.2, R.sub.3 is phenyl or cyclohexyl and R.sub.4 is H, or R.sub.3 and R.sub.4 together are cyclohexylidene, n is 2 or 3, and A is monoalkylamino or dialkylamino, each alkyl radical having 1 to 4 carbon atoms, or amino derived from a cycloalkylamine of 5 to 7 chain members which may contain an additional hetero-atom, provided that each of R.sub.1 and R.sub.2 is not H if R.sub.3 is phenyl or cyclohexyl and R.sub.4 is H, racemates, optical isomers, and their pharmaceutically acceptable acid addition salts and quaternary ammonium salts obtained with alkyl halides, have marked activity as peripheral vasodilators, platelet aggregation inhibitors, spasmolytic agents, coronary and cerebral vasodilators, and papaverine-like activity.

REFERENCES:
patent: 2541634 (1951-02-01), Blicke
Lands et al., J. Pharmacol. & Exptl. Thereof. 117 : 334, 339 (1956).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Substituted thienyl-acetic acid esters does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted thienyl-acetic acid esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted thienyl-acetic acid esters will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1478337

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.