Substituted thieno[3,2-C]pyridine-7-carboxylic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S301000

Reexamination Certificate

active

07994321

ABSTRACT:
There are provided compounds of the formulawherein R1, R2, R3, X, Y, Q, Ring A and Ring B are as described.The compounds exhibit activity as anticancer agents.

REFERENCES:
patent: 2005/0256154 (2005-11-01), Luk et al.
patent: WO 2004/100947 (2004-11-01), None
patent: WO 2005/010009 (2005-02-01), None
patent: WO 2005/105809 (2005-11-01), None
patent: WO 2006/106326 (2006-10-01), None
Michelotti et. al. “Two classes of p38a MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes” Bioorganic & Medicinal Chemistry Letters 2005, 15, 5274-5279.
Jiang et. al. “3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors.” Bioorganic & Medicinal Chemistry Letters 2007, 17, 6378-6382.
Liu et. al. “Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors” Bioorganic & Medicinal Chemistry Letters 2006, 16, 2590-2594.
Miyazaki et. al. “Design and effective synthesis of novel templates, 3,7-diphenyl-4- amino-thieno and furo-[3,2-c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases” Bioorganic & Medicinal Chemistry Letters 2007, 17, 250-254.
Mulvihill et. al. “Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors” Bioorganic & Medicinal Chemistry 2008, 16, 1359-1375.
Mulvihill et. al. “1,3-Disubstituted-imidazo[1,5-a]pyrazines as insulin-like growth-factor-I receptor (IGF-IR) inhibitors” Bioorganic & Medicinal Chemistry Letters 2007, 17, 1091-1097.
Blackburn et. al. “Discovery and optimization of N-acyl and N-aroylpyrazolines as B-Raf kinase inhibitors” Bioorganic & Medicinal Chemistry Letters 20 (2010) 4795-4799.
Strumberg and Seeber, Onkologie, 2005, 28: 101-107.
Beeram et al, J. Clin. Oncol. 2005, 23: 6771-6790.
Bollag et al, Current Opinion in Investigational Drugs, 2003, 4: 1436-1441.
Sharma et al, Cancer Res. 2005, 2412-2421.
Roberts et al, Cancer Research, 2005, 65(3), 957-966.
Ho et al., J. Med. Chem., 2005, 48, 8163-8173.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Substituted thieno[3,2-C]pyridine-7-carboxylic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted thieno[3,2-C]pyridine-7-carboxylic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted thieno[3,2-C]pyridine-7-carboxylic acid derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2705515

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.