Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucom

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549 50, A61K 3138, C07D33332

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active

048943908

ABSTRACT:
Aromatic sulfonamides useful in the treatment of elevated intraocular pressure having the structural formula: ##STR1## wherein A, R, R.sup.1, and R.sup.2 are as hereinafter defined, as well as the pharmaceutically and ophthalmologically acceptable salts thereof.

REFERENCES:
patent: 3733322 (1973-05-01), Wright
patent: 4665090 (1987-05-01), Graham
patent: 4668697 (1987-05-01), Shepard et al.
Kvitko et al. J. Org. Chem. 12, 1550 (1976).

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