Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antigla

Details Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antigla Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antigla

1990-10-01

1992-03-03

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544 48, 5142245, A61K 3154, C07D51300

Patent

active

050933329

ABSTRACT:
Thieno[2,3-b][1,4]thiazine-6-sulfonamides having the structural formula: ##STR1## wherein Z, R.sup.1, R.sup.2, and n are as hereinafter defined, are carbonic anhydrase inhibitors useful in the topical treatment of elevated intraocular pressure and glaucoma.

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patent: 4820848 (1989-04-01), Poticello et al.
patent: 4824968 (1989-04-01), Ponticello et al.
patent: 4863922 (1989-09-01), Baldwin et al.
Paulmier, C., Tetrahedron Lett., 1978, 21, 1797-1800 (I) French Language.
Paulmier, C., Bull. Soc. Chim. Fr., 1980, II, 151-156 (II) French Language.

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