Substituted thiazepines as central nervous system agents

Details Substituted thiazepines as central nervous system agents Substituted thiazepines as central nervous system agents

1991-08-27

1993-04-27

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540544, C07D 28106, A61K 3155

Patent

active

052062333

ABSTRACT:
Substituted thiazepines are described as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as antipsychotic and antidepressant agents as well as for treating cerebral ischemia or cerebral infarction.

REFERENCES:
Largent, et al. J. of Pharmacol. and Exp. Therapeutics, vol. 238(2) 1986 pp. 739-748.
Tam, Proc. Natl. Acad. Sci, USA 80 pp. 6703-6707, 1983.
The Merck Manual, (Rahway, N.J. Merck and Co., 1992) pp. 1614-1644.
The Merck Manual (Rahway, N.J. Merck and Co., 1981) pp. 1518-1522 and 1540-1541.
Guy et al., Drug Devol. Res. 3:245-252 (1983).
Lindstrom et al., Psychopharm. (1985) 86:241-243.
Chouinard et al., Psychopharm. (1984) 84:282-284.
Chouinard et al., Psychopharm. Bull. 22(1) 1985-pp. 267-271.
Rao, et al, Neuropharm. 29(12) pp. 1191-1197, 1990.
McLean, et al., Pharm. Biochem. and Behavior 8 97-99, 1978.
Bass, et al., J. Pharmacol. Exp. Therapeutics 186(1) 1973 pp. 183-198.
Walker, et al., Pharmacol. Rev. 1990, 42(4) pp. 355-402.
Kumar, Jain et al., Int. Clin. Psychopharm 1987(2) 129-133.
Rao et al., Neuropharm. 29(12) 1199-1204, 1990.
Pontecorvo et al., Brain Res. Bull., 26 pp. 461-465, 1991.
Lobner et al., Neuroscience Letters 117 (1990) 169-174.
Campbell et al., J. of Neuroscience 1989 9(10) 3380-3391.
Moore et al, Amer. Coll. Neuropsychopharm. Abstract, p. 149, (1985).

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