Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-07-12
2005-07-12
Davis, Zinna Northington (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S357000, C546S192000, C546S336000
Reexamination Certificate
active
06916830
ABSTRACT:
Substituted tetrahydroisoquinolines and related compounds are provided. Such compounds are ligands that may be used to modulate C5a receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological C5a receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies:
REFERENCES:
patent: 1308438 (2003-05-01), None
patent: 1318140 (2003-06-01), None
patent: WO 02/49993 (2002-06-01), None
Currie Kevin S.
Lee Kyungae
Mitchell Scott A.
Ohliger Robert
Zhang Lu-Yan
Davis Zinna Northington
Fidel Seth A.
Kadlecek Ann T.
Neurogen Corporation
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