Substituted tetrahydroisochinolines as MMP inhibitors,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S253050, C514S309000, C544S128000, C544S363000, C546S141000

Reexamination Certificate

active

07858619

ABSTRACT:
The present invention is directed to a compound of formula (I),wherein R1, R2, R3, R4, A, L and n are as defined herein, its pharmaceutical composition, preparation and uses as a MMP inhibitor.

REFERENCES:
patent: 5962471 (1999-10-01), Schudok et al.
patent: 102004031850 (2006-01-01), None
patent: WO 97/18194 (1997-05-01), None
patent: WO 03/016248 (2003-02-01), None
Ma, Dawei, et al., Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors, Bioorganic and Medicinal Chemistry Letters 14 47-50, Jan. 2004.

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