Substituted tetrahydrobenzazepinones

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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540527, C07D22316, A61K 3153

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active

054849179

ABSTRACT:
The present invention relates to novel substituted hexahydroazepinones and tetrahydrobenzazepinones of the formulae ##STR1## wherein R.sup.1, Z.sup.1, Z.sup.2, W.sup.1, W.sup.2, Y.sup.1 and Y.sup.2 are as defined below, and to novel intermediates used in the synthesis of such compounds.
Such compounds are useful in the treatment and prevention of gastrointestinal disorders, pain and anxiety disorders.

REFERENCES:
patent: 4767756 (1988-08-01), Das et al.
patent: 5206234 (1993-04-01), Shah et al.
Bock et al., Bioorganic and Medicinal Chemistry Letters, vol. 3 (5), 871-4 (1993).

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