Substituted tetrahydro-1 H -pyrazolo [3,4- c ]pyridines...

Details Substituted tetrahydro-1 H -pyrazolo [3,4- c ]pyridines... Substituted tetrahydro-1 H -pyrazolo [3,4- c ]pyridines...

2006-05-23

2008-10-14

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S120000

Reexamination Certificate

active

07435820

ABSTRACT:
Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.

REFERENCES:
patent: 2827861 (2003-01-01), None
patent: 02/12242 (2002-02-01), None
patent: WO 02/12242 (2002-02-01), None
patent: WO 03/024967 (2003-03-01), None
patent: WO 2004/064778 (2004-08-01), None
Hetian et al., The journal of biological chemistry, 2002, vol. 277, pp. 43137-43142.
Dorte Krehan et al., Aza-THIP and Related Analogues of THIP as GABAc Antagonists, Bioorganic & Medicinal Chemistry (2003, pp. 4891-4896, vol. 11).
Povl Krogsgaard-Larsen et al., GABA Agonists. Synthesis and structure-activity studies on analogues of isoguvacine and THIP, Eur. J. Med. Chem.- (1979, pp. 157-167, vol. 14, No. 2).

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