Substituted sulfonamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514252, 544363, 544364, 544368, 544376, 544380, A61K 31495, C07D40100, C07D41300, C07D24104

Patent

active

055654576

ABSTRACT:
The compounds are N-(2,3,4-trimethoxybenzyl)piperazines N'-substituted by a radical containing a sulfonamide group, and pharmaceutically tolerable salts thereof, useful for treating myocardial ischaemic pathologies, cerebral vascular accident and manifestations of deficiency associated with chronic cerebral circulatory disorders.
A compound disclosed is : N-benzyl-N-{3,3-dimethyl-4-[4-(2,3,4-trimethoxybenzyl) piperazin-1-yl]butyl}-(isoquinolin-5-yl)sulfonamide and its fumarate.

REFERENCES:
patent: 4948892 (1990-08-01), Tanabe et al.
patent: 5326870 (1994-07-01), Kajihara et al.

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