Substituted (sulfinic acid, sulfonic acid, sulfonylamino or comp

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514307, 514309, 514329, 514343, 514422, 514426, 540606, 546141, 546223, 546281, 546139, 5462764, 548527, 548557, C07D40102, A61K 3140, A61K 31435

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active

059589183

ABSTRACT:
The compounds of formula I exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More especially, they are inhibitors of the activity of Factor Xa. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, and their use, which are for treating a patient suffering from, or subject to, physiological condition which can be ameliorated by the administration of an inhibitor of the activity of Factor Xa.

REFERENCES:
patent: 5612353 (1997-03-01), Ewing et al.
patent: 5731315 (1998-03-01), Ewing et al.
Valerio et al, Synthesis, vol. 10, pp. 786-789, 1988.

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