Substituted quinoxalyl-imidazolidine-2,4-diones, processes for t

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514250, 544231, 544344, 544347, 544353, 544354, 544356, A61K 31495, C07D40102, C07D40104, C07D40114

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active

049435760

ABSTRACT:
Substituted quinoxalyl-imidazolidine-2,4-diones, processes for their preparation, their use as medicaments and pharmaceutical preparations 5-Quinoxalyl-imidazolidine-2,4-diones of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meanings given, and physiologically tolerated salts thereof and processes for their preparation are described. The compounds inhibit aldose reductase and can be used as medicaments.

REFERENCES:
patent: 4734407 (1988-03-01), Schmidt et al.
P. F. Kador et al., J. Med. Chem., vol. 28, pp. 841-849 (1985).

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