Substituted quinolone carboxylic acids, their derivatives,...

Details Substituted quinolone carboxylic acids, their derivatives,... Substituted quinolone carboxylic acids, their derivatives,...

2008-04-08

2008-04-08

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S220000, C514S250000, C514S312000

Reexamination Certificate

active

10514808

ABSTRACT:
Substituted quinolone carboxylic acids and their derivatives are described. These compounds modulate the effect of γ-aminobutyric acid (GABA) via a novel site on the GABAAreceptor complex in a therapeutically relevant fashion and may be used to ameliorate CNS disorders amenable to modulation of the GABAAreceptor complex.

REFERENCES:
patent: 4390541 (1983-06-01), Goldsworthy et al.
patent: 6248739 (2001-06-01), Turner et al.
patent: 6413956 (2002-07-01), Albaugh et al.
patent: 0 055 068 (1982-06-01), None
patent: WO 00/68202 (2000-11-01), None
Piganeau, J Mol Biol, vol. 312, pp. 1177-1190, 2001.
Kalkote, Tetrahedron Letters, vol. 37, No. 37, pp. 6785-6786, 1996.
Uno, Toshio et al. “Synthesis of Antimictobial Agents. I. Syntheses and Antribacterial Activities of 7-(Azole substituted) quinolones” Journal of Medicinal Chemistry. Dec. 1987, vol. 30, No. 12, pp. 2163-2169.

Affiliated with

Also associated with

Rating

Substituted quinolone carboxylic acids, their derivatives,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted quinolone carboxylic acids, their derivatives,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted quinolone carboxylic acids, their derivatives,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3956248