Substituted quinoline derivatives, a process for their preparati

Details Substituted quinoline derivatives, a process for their preparati Substituted quinoline derivatives, a process for their preparati

1995-08-14

1998-08-25

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514313, 546158, 546159, C07D215227, C07D21538, A61K 3147

Patent

active

057983658

ABSTRACT:
Compounds of the formula I, ##STR1## and also their tautomeric forms of the formula Ia, ##STR2## in which the substituents R.sup.1 to R.sup.6 and X have said meanings, exhibit antiviral activity.

REFERENCES:
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Kaneko, C. et al., Photochemistry of Heterocyclic Compounds. (4) ..sup.1) Solvent Effects in the Photolysis of Tetrahydroacridine 10-Oxide Derivatives.sup.2), Chem. Pharm. Bull., 17:1290-1294(1969).
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Daruwala et al., ".beta.-Amino Ketones. Synthesis and Some Biological Activities in Mice of 3,3-Dialkyl-1,2,3,4-Tetrahydro-4-quinolinones and Related Mannich Bases", Journal of Medicinal Chemistry, 17(8):819-824(1974).
F.D. Lewis et al., "Spectroscopy and Photochemistry of 2-Quinolones and Their Lewis Acid Complexes," J. Org. Chem., vol. 56, No. 18, (1991), pp. 5311-5318.
G. Himbert et al., "Influence Of Substituents In p-, m-, and o-Position Of The Arene Onto The Intramolecular Diels-Adler Reaction of Allenecarboxylic Acid Anilides and Phenyl Esters," Chem. Ber., vol. 122, No. 6, (1989), pp. 1161-1173.

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