Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Reexamination Certificate
2007-05-22
2007-05-22
Wilson, James O. (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
C544S224000, C544S242000, C546S001000, C546S026000, C546S134000, C514S211010
Reexamination Certificate
active
10607530
ABSTRACT:
The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b):enantiomers, diastereomers, salts and solvates thereof wherein R1, R2, R3, R4, R5, and R7are as defined herein. The invention further includes a method of CCR5-mediated disorders employing such compounds.
REFERENCES:
patent: 5494908 (1996-02-01), O'Malley et al.
patent: 6169088 (2001-01-01), Matsuno et al.
patent: 6344450 (2002-02-01), Bisacchi et al.
patent: 1234397 (1999-10-01), None
patent: 0882717 (1998-04-01), None
patent: 0882717 (1998-12-01), None
patent: 1013276 (2000-06-01), None
patent: 1308439 (2003-05-01), None
patent: 84902 (1962-06-01), None
patent: 84902 (1965-05-01), None
patent: WO 98/27815 (1998-07-01), None
patent: WO 99/31086 (1999-06-01), None
patent: WO 02/22599 (2002-03-01), None
patent: WO 02/072578 (2002-09-01), None
patent: WO 02/094203 (2002-11-01), None
Agrawal et al., “Antiparasitic Agents . . . ”, Indian journal of Chemistry, Vo. 26 B, Jun. 1987, pp. 550-555.
Agrawal V K et al, “Antiparasitic Agents: Part VI—Synthesis of 7-Chloro-4-(4-substituted-phenylamino)- & 7-Chloro-4-(4-substituted-Piperazin-1-YL) Quinolines as Potential Antiparasitic Agents”,Indian Journal of Chemistry, (1987) 26B:550-555.
Kireev D et al, “Molecular modeling and quantitative structure-activity studies of anti-HIV-1 2-heteroarylquinoline-4-amines”European Journal of Medicinal Chemistry, (1995) 30:395-402.
Tripathi, R.C. et al,Indian J. Chemistry, (1995) 34:164-166 (abstract).
Dunning Laura
Jaroch Stefan
Kochanny Monica J.
Lee Wheeseong
Lian Xiongdong
Millen White Zelano & Branigan P.C.
Schering Aktiengesellschaft
Ward Paul V.
Wilson James O.
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