Substituted pyrroles

Details Substituted pyrroles Substituted pyrroles

1992-09-21

1994-03-08

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514278, 546 18, 546 70, A61K 3144, C07D47100

Patent

active

052927474

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X, m, n, p, and q are as set forth in the specification, as well as pharmaceutically acceptable salts of acidic compounds of formula I with bases and of basic compounds of formula I with acids, which are useful in the control or prevention of inflammatory, immunological, oncological, bronchopulmonary, dermatological or cardiovascular disorders or for the treatment of asthma, AIDS or diabetic complications or for the stimulation of hair growth are described.

REFERENCES:
patent: 4107297 (1978-08-01), Omura et al.
patent: 5057614 (1991-10-01), Davis et al.
Chem. Abstr. col. 113, No. 11 97381n Sep. 10, 1990.
Tetrahedron Lett. 1990 31(16), 2353-6, David Peter D.
Chem. Abstr. 114(23) 228726z (1990).
Chem. Abstr. 112(11) 98378h (1989).
Chem Abstr. vol. 93 p. 503, 1980, 66027r.
Chem. Abstr. vol. 98 p. 585, 1983, 215863t.
Chem. Abstr. 104: 207579g vol. 104 p. 789, 1986.
Chem. Abstr. 101:55460j vol. 101 p. 654 1984.
Chem. Abstr. 102:6236c vol. 102 p. 567, 1985.
Chem. Abstr. 113:40560r (1990).
Chem Abstr. 114:81582p (1990).
Tetrahedron 47 (26) 4645-64 (1991).

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